PIM1 and acute myeloid leukemia: For this reason, we compared SEL24-B489 head-to-head with a selective PIM inhibitor (AZD1208) and a selective FLT3-ITD inhibitor (AC220) in a panel of AML cell lines with FLT3-ITD (MV-4-11, MOLM-13) or unmutated kinase (FLT3-WT: KG-1, MOLM-16).