BCL2L1 and hepatocellular carcinoma: In agreement, sorafenib-resistant cells Hep3B were sensitive to ABT-263 alone (Figure 4C), while BCL-xL inhibitor A-1155463 did not kill resistant hepatoma cells preferentially, as observed in Hep3B R (Figure 4D) and HepG2 R cells (Supplementary Figure 4).