Survival curves were calculated according to univariate analysis (Table 2) and the Kaplan–Meier method by evaluating the age (≤ 60 vs > 60 years), sex, MG, invasion phenotype, invasion localization (capsular vs extra-capsular), tumor dimensions ≤ 5 cm or > 5 cm, radicality and CTLA-4 mRNA expression. The gene discussed is CTLA4; the disease is myasthenia gravis.