LCN2 and acute kidney injury: Similarly, our study also showed that the diagnostic effectiveness of UmtDNA (COX3: AUC = 0.767; ND1: AUC = 0.774) better distinguished no AKI and AKI compared with the NGAL (AUC = 0.751) and KIM-1(AUC = 0.694) (Supplementary Figure5).