GSDME and invasive ductal breast carcinoma: Remarkably, those 10 CpGs are all located in or upstream of the putative gene promoter region and not in the gene body of DFNA5. Despite the higher DFNA5 promoter methylation in the lobular adenocarcinomas, the DFNA5 expression was also significantly higher in the lobular compared to the ductal adenocarcinomas.