MGMT and malignant glioma: Interestingly, ZEB1, a regulator of EMT, plays an important role in key features of cancer stem cells including the regulation of stemness and chemoresistance induction through transcriptional regulation of O-6-Methylguanine DNA Methyltransferase (MGMT) via miR-200c and c-MYB in malignant glioma [68].