In a Caucasian population study, Ala1369Ser was correlated with Glu23Lys, where for every K allele of KCNJ11 gene found there was A allele of ABCC8, thus constituting a possible haplotype (Florez et al., 2004), whereas several studies and meta-analyses showed the association of KCNJ11, but not of ABCC8 polymorphisms, with susceptibility to type 2 diabetes (van Dam et al., 2005; Gong et al., 2012). This evidence concerns the gene KCNJ11 and type 2 diabetes mellitus.