Maackia amurensis agglutinin (MAA, a lectin recognizing α2–3-terminal sialic acids) binding to serum PSA was significantly higher (5.3-fold) for prostate cancer samples than for healthy controls, suggesting that a combined analysis of serum PSA levels and glycoprofiling of PSA has a potential for improved detection of prostate cancer [89]. The gene discussed is KLK3; the disease is Familial prostate cancer.