With the intersection of these 53 candidate lincRNAs with relative HCC genomic gains and the 1082 lincRNAs upregulated in the TCGA cohort of 50 paired HCC tissues and adjacent non-tumour (NT) tissues, four lincRNAs were identified, namely, LINC01138, PVT1, RP11-14N7.2 and RP11-30J20.1 (Fig. 1a and Supplementary Fig. 1a, b). The gene discussed is PVT1; the disease is hepatocellular carcinoma.