Overexpression of IGF2BP1 or IGF2BP3 could increase the half-life and steady-state level of LINC01138; whereas, the depletion of IGF2BP1 or IGF2BP3 resulted in a decreased half-life and RNA level of LINC01138 (Fig. 7b), revealing that IGF2BP1 and IGF2BP3 specifically regulate the stability of LINC01138 in the HCC cells. The gene discussed is IGF2BP3; the disease is hepatocellular carcinoma.