To assess the clinical significance of ZFAS1 in bladder cancer patients, we analyzed the correlation between ZFAS1 expression and clinical parameters in 102 bladder cancer cases, and found the expression level of ZFAS1 was positively associated with clinical stage, muscularis invasion, lymph node metastasis, and distant metastasis. The gene discussed is ZFAS1; the disease is urinary bladder cancer.