We have also analyzed concentrations of chemokines for neutrophils IL-8, CXCL1, and CXCL2, as well as Th17 cytokines IL-17A, IL-17F, and IL-22 in CSF and serum in prospectively recruited TBE patients, to assess their peripheral and intrathecal expression, concentration gradients, and relation to the CSF inflammatory parameters. The gene discussed is CXCL2; the disease is tick-borne encephalitis.