INS and Insulin resistance: Carriers of the major allele T had lower insulin levels, as estimated by ΔI30/ΔG30 (p = 0.008) and ΔI120/ΔG120 values (p = 0.017), than noncarriers, even after adjusting for insulin resistance (p′ = 0.004 and p′ = 0.006, resp).