Of those who reported only a family history of thyroid disease (i.e., no personal history) (n = 24), only 16.66% (n = 4) had anti-TPO or anti-Tg antibodies in their sera (two patients carried anti-TPO antibodies only, one patient carried anti-Tg Abs only, and one carried both anti-TPO and anti-Tg antibodies). Here, TPO is linked to thyroid gland disorder.