Most study regarding the mechanism for the protection of GLXB on I/R-induced myocardial infarction has focused on its effect on apoptosis, oxidative stress and inflammation, and the signaling pathways proposed include NF-κB, TGF-β1, and MAPKs (Ding et al., 2013, 2016). This evidence concerns the gene TGFB1 and myocardial infarction.