In this work, for the first time a wireless treatment based on piezoelectric nanoparticles has been exploited to remotely deliver electric stimulations to breast cancer cells; chronic piezoelectric stimulation was able to upregulate the mature mRNA expression of KCNJ6 gene encoding for Kir3.2 inward rectifier K+ channels, to affect Ca2+ homeostasis, and finally to induce the arrest of the cell cycle in G0/G1 phases. The gene discussed is KCNJ6; the disease is breast carcinoma.