CXCL13 and chronic obstructive pulmonary disease: mRNA expression of CH25H and the pro‐inflammatory chemokine CXCL8 were significantly upregulated in emphysematous regions rather than non‐emphysematous regions of COPD patient lungs, while in contrast to recent findings (Faner et al, 2016), CXCL13 expression did not differ (Fig 1D).