In the aqueous humor samples of fungal keratitis group, the levels of IL-1β, IL-6, IL-8, and IFN-γ were found to be significantly increased, as compared with the control group (P = 0.012 for IL-1β, P < 0.001 for IL-6, P < 0.001 for IL-8, and P = 0.001 for IFN-γ). The gene discussed is IFNG; the disease is fungal keratitis.