Applying a set of 1826 fully annotated prostate cancers, Gannon and colleagues showed a significant association between an increase in the nuclear frequency of NF-κB RELA and Gleason score, which is used to score prostate cancer grade, although the contribution of NF-κB RELA to a post-surgical predictive model appears modest [61]. Here, NFKB1 is linked to prostate cancer.