DKK3 is reported to be a putative antagonist of the Wnt/β‐catenin signalling pathway,7 and activation of this pathway has been implicated in the pathogenesis of leukaemia.24, 25, 26 To explore the effects of MYCN on the Wnt/β‐catenin signalling pathway, we measured the protein levels of p‐GSK3β, GSK3β and both cytoplasmic and nuclear β‐catenin in Nalm6 and BALL‐1 cells by Western blotting. This evidence concerns the gene MYCN and leukemia.