FISH analysis with a multiprobe CLL panel did not detect loss of MYB (6q23), ATM (11q22), TP53 (17p13), and chromosome band 13q14.3, nor was there any indication of IGH-BCL2, IGH-CCND1 or other IGH splits or extra copies of chromosome 12 (data not shown). The gene discussed is MYB; the disease is B-cell chronic lymphocytic leukemia.