LIMD1 and head and neck squamous cell carcinoma: Deletion frequency of LIMD1 was high (33%) in dysplastic lesions and became comparable in stage I/ II (33–37%) followed by gradual increase in subsequent stages (III/ IV) (47–60%) (Fig 4B ii).Identically, incidence of deletion of CDC25A in dysplasia (40%) was comparable to HNSCC stage I/II (31–41%), with successive increase in stage III/ IV (52–53%) (Fig 4B iii).