TMPRSS2 and Familial prostate cancer: Recently, expression analysis of different prostate cancer biomarkers, such as TMPRSS2:ERG (fusion of the androgen receptor-responsive promoter of the serine protease gene, TMPRSS2, with the transcription factor ERG), alpha-methylacyl-CoA racemase (AMACR), and prostate cancer gene 3 (PCA3), in urine sediments has been reported [8–11].