TIMP1 and myocardial infarction: Specifically, we identified TIMP1, APOD and NAD+, among others, to have been highly propagated.39, 40, 41 It is known that TIMP1 inhibits metalloproteinases and it was shown to directly mediate protection from I/R injury in a rat model of myocardial infarction.39 Other genes, such as BCLA1, MT2, Saa3 and Usp17la, have likewise been demonstrated to exercise positive influences on cell survival.42, 43, 44, 45, 46