Patients with HIV+/HCV co‐infection characteristics were: age (Mean 46.93, SD = 7.91 years), Depression Scale [BDI‐II] scores (Mean 12.47, SD = 9.25), CSF Viral (Mean 1.51, SD = 1.45), CD4 Nadir (Mean 363.36, SD = 252.02), current CD4 (Mean 679.83, SD = 435.79), and CNS Penetration‐Effectiveness (CPE) of Antiretroviral Therapy (ART) (Mean 3.5, SD = 2.76). This evidence concerns the gene CD4 and coinfection.