CTSE and fibrosis: They identified the largest overlap in differentially expressed genes between lung transcriptome of bleomycin-induced fibrosis and IPF human lungs and identified 12 genes (C6, CTHRC1, CTSE, FHL2, GAL, GREM1, LCN2, MMP7, NELL1, PCSK1, PLA2G2A, and SLC2A5) as translational markers of disease activity.