CD8A and neoplasm: A recent study shows that high number of cytotoxic lymphocytes such as natural killer (NK) or CD8+ T cells in the tumors correlate with favorable prognosis, whereas high infiltration of myeloid cells such as eosinophils, tumor-associated macrophages (TAM) and neutrophils is associated with poor prognosis in most solid tumors (Gentles et al., 2015).