Diabetes mellitus is a chronic metabolic disorder characterized by derangements in carbohydrate, protein and lipid metabolisms, due to defective or deficiency in insulin secretion and action.1 Insulin is a hormone secreted by the beta cells of the Islets of Langerhans of the pancreas, it helps in glucose uptake by the cells, thereby prevents increase in fasting blood glucose levels.2 The gene discussed is INS; the disease is diabetes mellitus.