AOPEP and type 2 diabetes mellitus: The notable GWAS studies in Chinese populations have essentially offered several loci mapping to DENND1A, THADA, LHCGR, FSHR, INSR, TOX3, YAP1, RAB5B, c9orf3, HMGA2, and SUMO1P1/ZNF217 involved in steroidogenesis, gonadotropin action and regulation, follicular development, insulin signaling and type 2 diabetes mellitus (T2DM), calcium signaling, and endocytosis [147, 148].