Administration of corticosteroids suppresses the hypothalamic-pituitary-adrenal (HPA) axis, and ways to assess this include the following: morning serum cortisol level, synthetic adrenocorticotropic hormone (ACTH) stimulation test, ovine corticotrophin releasing hormone (CRH) stimulation test, and insulin-induced hypoglycemia [18]. The gene discussed is POMC; the disease is Hypoglycemia.