Several molecules, such as soluble cytokines and growth factors, may regulate myocardial fibrosis by a complex set of interactions, and the profibrotic protein transforming growth factor-beta (TGF-β) is one of those major mediators since it induces fibroblasts and other cell types to synthesize the extracellular matrix (ECM) [8]. Here, TGFB1 is linked to Myocardial fibrosis.