Very interestingly, five SNP in the TGFB1 gene of known or suggested functional significance (−988 C>A, −800 G>A, −509 C>T, +10 T>C, and +263 C>T) were studied in a Peruvian and a Colombian population seropositive for Chagas disease versus seronegative. Here, TGFB1 is linked to Chagas disease.