CD8A and disseminated peritoneal leiomyomatosis: Excessive inhibition of Th1 cells, EMCD8+ T cells and EBV-specific CD8+ T cells by MTX at the time of LPD development, and their restoration after MTX cessation appear to be features specific to the pathogenic and regression mechanism of “regressive LPD” (Figure 9), since a decrease in the proportion and absolute number of these cell subsets was not observed in persistent LPD.