Supplementation of the stimulating media (CD3/CD28/CAB) with TGFβ + IL6 + anti-IL4 antibody attenuated the IL-22 production of healthy- and PsA-derived but not those of the RA-derived T cells (p < 0.05 and p < 0.05, respectively) and the IL-17A production of the PsA T cells (p < 0.01). The gene discussed is IL6; the disease is rheumatoid arthritis.