IL10 and viral infectious disease: However, a brief look at intrathecal inflammation in CNS infections affords the opportunity to compare the host inflammatory response to autoantigens vs exogenous microbial antigens (Table 7) (134–159) There were more similarities than differences, given increased CSF concentrations of IL-6, IL-8, and IL-10, but no clear split between bacterial vs viral diseases with the exception of subsclerosing panencephalitis, which stood apart (normal IL-10).