AQP4 and Autoimmunity: Specifically, antinuclear antibodies were found in only 7% of MOG-IgG patients (versus 43% of AQP4-IgG patients) (48), and coexisting autoimmune conditions were reported in only 11% of MOG-IgG individuals (versus 45% of AQP4-IgG subjects) in another series (49).