Furthermore, the expression of PI3K/Akt/mTOR pathway-related proteins was also altered in xenograft tumor tissue isolated from QLXZD-treated mice, with the phosphorylation of Akt (T308), mTOR (Ser2448), and p70S6K (T389) being inhibited in the QLXZD-treated group. The gene discussed is AKT1; the disease is neoplasm.