Interestingly, the DNM2 gene, which we revealed as down-regulated in our sALS patient samples, was also previously found to be mutated in Charcot-Marie-Tooth neuropathy type CMT2M, a motor and sensory neuropathy primarily affecting peripheral nerves (Züchner et al., 2005) and in centronuclear myopathy (CNM), presenting with primary damage in skeletal muscles (Bitoun et al., 2005). This evidence concerns the gene DNM2 and Sensory neuropathy.