As shown in Fig. 2, we discovered the association of the BCL3, PVRL2 and TOMM40 mutations with TC (rs2965101, rs4803748, rs2965169, rs8100239, rs519113, rs6859, rs157580, rs2075650 and rs439401), TG (rs2965101, rs8100239, rs10402271, rs3810143, rs6859, rs283810 and rs157580), LDL-C (rs2965101) in dyslipidemia group; and with TC (rs2965169, rs519113 and rs157580), TG (rs2965101, rs8100239, rs6859 and rs157580) in the normal group (P < 0.004–0.001); respectively. The gene discussed is NECTIN2; the disease is metabolic syndrome.