In a previous study, we have found that the BRCA2 rs9534275 SNP modulated serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), apolipoprotein (Apo) B levels, and the ApoA1/ApoB ratio in the hypercholesterolemic subjects15, but little is known about the relationship between dyslipidemia and other gene polymorphisms. Here, APOB is linked to metabolic syndrome.