In contrast, other receptors subtypes involved in the function of different pituitary cell types, such as gonadotropin-releasing hormone receptor (GnRHR), corticotropin-releasing hormone receptor (CRHR1) or vasopressin receptor (AVPR1b) were not noticeably expressed in somatotropinoma samples (Fig. 3D). This evidence concerns the gene CRHR1 and growth hormone-producing pituitary gland neoplasm.