MUC5B and lung adenocarcinoma: We observed that high expression of MUC5B mRNA was significantly associated with poor OS (n = 720, hazard ratio (HR) = 1.48, 95% confidence interval (CI) = 1.11–1.97, P = 0.007) and progression-free survival (n = 461, HR = 1.74, 95% CI = 1.19–2.56, P = 0.004) in patients with lung adenocarcinoma (Fig. 7c, d).