Functional enrichment analysis of the DRGs specific to the Z-DAN-11 treated cancer cells using IPA showed significant association of these genes (Tubb, Tuba, c-Jun, Tp53, Ddit3, Tgfbi etc.)in cell cycle and cell death-related processes (Fig. 3c,d), corroborating with our experimental validations (Fig. S3a-b). This evidence concerns the gene JUN and cancer.