Our results are in line with previous studies, reporting TRIB2 upregulation in response to survival factor withdrawal in primary T-cells and erythroleukaemia cells43, miR155 induction in acute myeloid leukaemia cells44 and cisplatin treatment in ovarian cancer cells6, which all associated with activation of the apoptotic pathway. This evidence concerns the gene TRIB2 and acute myeloid leukemia.