CNOT1 and liver cancer: Recently, a study reported that in human liver cancer cells, insulin-like growth factor 2 mRNA binding protein (IGF2BP), also known as IMP1 specifically interacts with the lncRNA highly upregulated in liver cancer (HULC) and promotes the decay of HULC through Ccr4-Not 1 (CNOT1)-mediated deadenylation [29].