In univariate analysis, TNFα < 2857.6 pg/mL (OR 7.86, 95%CI 2.27–27.22, P < 0.01), IP-10 < 333.4 pg/mL (OR 4.30, 95%CI 1.99–9.28, P < 0.01), IL-12 < 0.30 pg/mL (OR 2.78, 95%CI 1.35–5.72, P < 0.01), IL-10 > 57.0 pg/mL (OR 2.52, 95%CI 1.23–5.16, P = 0.01), and IL-8 > 1786.4 pg/mL (OR 5.00, 95%CI 2.36–10.60, P < 0.01) were associated with delirium. This evidence concerns the gene CXCL10 and delirium.