(2016) reported that approximately 15% of circulating conventional memory cells were CX3CR1int following acute viral infection (LCMV and vesicular stomatitis virus [VSV]) and that CX3CR1int displayed some features closer to CX3CR1 neg TCM cells (similar proliferation, CD27+, and CD127+) while other functional abilities (IL-2 production, cytotoxicity, and lymph node [LN] homing) were intermediate between CX3CR1hi TEM and CX3CR1neg TCM cells. Here, IL2 is linked to viral infectious disease.