The expression of genes associated with M2 monocytes (TGM2 (Transglutaminase 2), PDL2, CD206, CCL13), regulatory monocytes (IL-10, TGF-β) and angiogenesis (MMP9 (Matrix metallopeptidase-9), and VEGF (Vascular endothelial growth factor)) were significantly induced in all three different cancer cell line- exposed monocytes when compared to unexposed monocytes (Fig 1A and S2 Fig). The gene discussed is MMP9; the disease is cancer.