CD4 and cancer: While exposure to mf did not alter the ability of monocytes to induce T cell proliferation, exposure to MDA and the other two cancer cell lines (U87 and OVCAR; S5 Fig) significantly diminished their ability to promote allogeneic and autologous CD4+ (Fig 5A and 5B), and allogeneic CD8+ (Fig 5A) T cell proliferation.