SUZ12 and head and neck squamous cell carcinoma: Interestingly, we treated stable shSUZ12 cells with 5‐FU, a common chemotherapeutic agent for HNSCC and found that cells with SUZ12 silencing had enhanced chemosensitivity to 5‐FU as evidenced by significant lower OD values in shSUZ12 cell treated with 5‐FU as compared with shSUZ12 cells or cells treated with 5‐FU alone (Figure 5C,D).