Follicular maturation is dependent on the development of follicle-stimulating hormone (FSH), and FSH receptor (FSHR) has been found in the ovarian surface epithelium (OSE) and in some ovarian cancer cell lines and tissues; above all, the distribution of FSHR is limited to the reproductive system (Papadimitriou et al., 2016; Perales-Puchalt et al., 2017). The gene discussed is FSHR; the disease is ovarian cancer.