Since an increased frequency of subclinical atherosclerosis assessed by carotid US was found in AS without clinically evident CV disease [4, 8] and a relationship between the CRP levels at the time of disease diagnosis and the presence of subclinical atherosclerosis was also disclosed in these patients [8], we assessed whether both the carotid US and the CRP at the time of disease diagnosis may improve the sensitivity to identify high CV risk among young AS patients in whom the RR charts was applied. Here, CRP is linked to atherosclerosis.