Another point reinforcing the pathogenetical link between AITD and SS is represented by the crucial role of the epithelial cells in orchestrating the tissue inflammation and the involvement of several regulatory chemokines, such as the IFN-γ-inducible protein 10 (IP-10/CXCL10) in initiating and perpetuating the autoimmune process. This evidence concerns the gene CXCL10 and synovial sarcoma.