In addition, our results observed that no significant difference was found in the protein expression levels of p53 and FasL between sham + NS group and TAC + NS group and QSYQ has no significant effect on the protein expression levels of p53 and Fas ligand (FasL) in TAC mice (see Supplementary Material online, Figure S1). This evidence concerns the gene FASLG and persistent truncus arteriosus.